News & Publications


A Novel Thiol-saccharide Mucolytic for the Treatment of Muco-obstructive Lung Diseases

Reference: Addante A et al., A novel thiol-saccharide mucolytic for the treatment of muco-obstructive lung diseases. Eur Respir J 2023; in press (

Towards a Better Mucolytic

Editorial by: Burton F. Dickey and Christopher M. Evans Eur. Respir J 2023; 61: 2300619

Mucus Plugs Occluding COPD Airways: A Review of Their Clinical Impact

Diaz A, Mucus plugs occluding COPD airways: A Review of their clinical impact. The 2023 International Workshop on Pulmonary Imaging; Philadelphia, PA, February 23 – 25, 2023

Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers

Reference: Dunican EM et al., Mucus plugs and emphysema in the pathophysiology of airflow obstruction and hypoxemia in smokers. Am J Respir Crit Care Med; Vol 203, Iss 8, pp 957–968, Apr 15, 2021

Luminal Plugging on Chest CT Scan, Association With Lung Function, Quality of Life, and COPD Clinical Phenotypes

Reference: Okajima Y et al., Luminal plugging on chest CT scan, association with lung function, quality of life, and COPD clinical phenotypes. CHEST; 158(1):121-130, 2020

Airway Mucus Function and Dysfunction

Reference: Fahy JV, Dickey BF, Airway mucus function and dysfunction. N Engl J Med;363:2233-47, 2010.